What Is Creatine Monohydrate?

Creatine Monohydrate is the world’s most researched performance supplement, with decades of clinical evidence supporting its role in regenerating ATP — the primary energy currency of muscle cells — during high-intensity exercise. Thorne’s Creatine Monohydrate uses CreaPure®, the highest purity creatine available, produced in Germany and tested for banned substances, ensuring the cleanest, most effective form of this foundational nutrient. Beyond sports performance, emerging research supports creatine’s role in brain energy metabolism and cognitive function.

Key Benefits

Increases muscle strength, power, and high-intensity exercise capacity
Supports faster recovery between training sessions
Promotes lean muscle mass during resistance training
Supports brain energy metabolism and cognitive function
NSF Certified for Sport — safe for competitive athletes

Who Should Take This?

Creatine Monohydrate is appropriate for athletes and active adults of all levels who want to improve performance and recovery, as well as older adults looking to preserve muscle mass and strength. It is also increasingly recommended for brain health, particularly in patients experiencing cognitive fatigue or those with neurological concerns.

How to Use

Serving Size: Take one rounded teaspoon (5 g) mixed into water, juice, or a protein shake once daily, or as directed by your healthcare provider.
Timing: Creatine can be taken any time of day; consistency matters more than timing. A loading phase is optional — steady daily use reaches saturation within 3–4 weeks.
Duration: Use consistently for best results; consult your provider for long-term use.
Stacking: Pairs well with other supplements in your provider’s protocol.

Our Doctors’ Take

Creatine is one of the few supplements with such overwhelming research support that we recommend it broadly — not just to athletes, but to active patients of all ages looking to preserve strength and support brain health. Thorne’s CreaPure® formulation gives us confidence in purity and potency. For patients doing physical rehabilitation or wanting to build resilience, creatine is a foundational tool.

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.