Berberine

What Is Berberine?

Thorne’s Berberine is a dual-action formula combining 450mg of Berberine HCl with 550mg of Berberine Phytosome — a patented phospholipid-bound form that significantly enhances absorption and bioavailability compared to standard berberine formulations. Berberine is a naturally occurring alkaloid found in several plants with a long history in traditional medicine and an extensive modern research base. The phytosome technology in this formula ensures patients receive the full therapeutic benefit that clinical studies have demonstrated for cardiovascular, metabolic, and gastrointestinal health support.*

Key Benefits

• Supports healthy blood sugar balance and insulin sensitivity already within normal range
• Promotes healthy cholesterol and triglyceride levels already in a normal range through AMPK pathway activation
• Supports cardiovascular health and healthy heart function through multiple metabolic mechanisms
• Helps maintain a balanced gut microbiome by supporting beneficial bacterial populations
• May support healthy immune function through its interaction with gut-associated immune tissue
• Phytosome form provides significantly enhanced bioavailability over standard berberine HCl alone

Who Should Take This?

Thorne’s Berberine is well suited for adults focused on metabolic and cardiovascular wellness, patients looking to support healthy blood sugar and insulin response as part of a dietary and lifestyle program, individuals seeking natural cardiovascular support, and those interested in gut microbiome balance from a botanical perspective. Our doctors recommend discussing berberine with your healthcare provider if you take prescription medications, as berberine may interact with certain drugs metabolized by the liver.

How to Use

• Serving size: Take 1 capsule two to three times daily with meals
• Timing: Always take with food — berberine is best absorbed with meals and taking it on an empty stomach may cause GI discomfort
• Duration: Typically used for 3-month cycles; evaluate response and consult with your provider about ongoing use
• Stacking: Combines well with Super EPA for cardiovascular support, FloraMend Prime Probiotic for gut microbiome balance, and Magnesium Bisglycinate for metabolic cofactor support

Our Doctors’ Take

Our doctors have followed the growing body of research on berberine with significant interest, particularly for patients managing metabolic health challenges alongside their chiropractic care. The phytosome form Thorne uses represents an important formulation advancement — standard berberine has notoriously variable absorption, and the phytosome technology meaningfully addresses this limitation. For patients motivated to take a proactive, natural approach to metabolic wellness, this is a well-designed option.*

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.