What Is GI Relief (formerly GI-Encap)?
GI Relief — formerly known as GI-Encap — is Thorne’s practitioner-trusted botanical formula for gastrointestinal comfort and gut lining support. Each serving delivers a synergistic blend of marshmallow root, aloe vera gel, deglycyrrhizinated (DGL) licorice, and slippery elm bark — four time-tested botanicals with a long history of use for soothing irritated mucous membranes, supporting gut lining integrity, and relieving digestive discomfort. With 180 capsules providing 90 servings, it offers a full therapeutic course in a single bottle.
Key Benefits
- Soothes and supports the integrity of the gastrointestinal mucosal lining throughout the digestive tract
- Helps relieve occasional bloating, gas, and abdominal discomfort associated with gut irritation
- Promotes healthy healing and recovery of the gut lining after periods of stress, travel, or dietary deviation
- DGL licorice supports a healthy gastric environment without the blood pressure concerns of whole licorice
- Marshmallow root and slippery elm provide demulcent (coating) properties to calm inflamed or irritated tissue
- Aloe vera gel supports healthy gut motility and a balanced intestinal environment
Who Should Take This?
GI Relief is an excellent fit for patients dealing with occasional heartburn, reflux, or upper GI discomfort, individuals with sensitive digestive systems who experience irritation after meals, patients working to restore gut lining health during a functional medicine or elimination protocol, anyone experiencing stress-related digestive symptoms, and patients recovering from periods of heavy NSAID use or dietary imbalance. Our doctors often incorporate this formula in comprehensive gut healing protocols.
How to Use
- Serving size: Take 2 capsules twice daily (4 capsules total per day) or as directed
- Timing: Best taken 20–30 minutes before meals so the botanicals can coat and prepare the GI lining before food arrives
- Duration: Typically used for 4–8 weeks as part of a targeted gut healing protocol; can be used ongoing at a lower dose for maintenance
- Stacking: Works synergistically with FloraMend Prime Probiotic for gut microbiome balance, Advanced Digestive Enzymes for improved digestion, and Super EPA to support a healthy GI inflammatory response
Our Doctors’ Take
Our doctors appreciate that GI Relief addresses the root physical concern — a compromised gut lining — rather than simply masking symptoms. The DGL licorice form is important for patient safety since it removes the glycyrrhizin compound associated with blood pressure effects, making this appropriate for long-term use. For patients presenting with digestive complaints alongside musculoskeletal issues, we often begin with gut healing as a foundational first step, since a healthy gut is essential for absorbing all other nutrients and supplements.*
*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.


















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