What Is NAC 500mg?
NAC 500mg by Thorne delivers N-acetyl-L-cysteine — a stable, bioavailable form of the amino acid cysteine that serves as the direct precursor to glutathione, the body’s most important intracellular antioxidant. By replenishing cysteine availability, NAC helps the body produce and recycle glutathione in the liver, lungs, and throughout the immune system. NAC has one of the most extensive research profiles of any amino acid supplement, with applications in liver health, respiratory support, detoxification, immune function, and antioxidant protection. Each bottle provides 90 capsules at an accessible price point.
Key Benefits
- Supports robust glutathione production — the body’s master antioxidant and primary detoxification molecule
- Promotes healthy liver function and detoxification pathways, particularly phase II liver detox
- Supports respiratory health by helping maintain healthy mucus viscosity and airway function
- Helps protect cells from oxidative stress caused by environmental toxins, pollutants, and metabolic byproducts
- Supports immune system resilience through its antioxidant and anti-inflammatory activity
- May help support healthy kidney function by protecting against oxidative damage
Who Should Take This?
NAC 500mg is well suited for adults focused on detoxification and liver support, patients with high toxin or chemical exposure (urban environments, occupational exposure), individuals supporting respiratory health, anyone undergoing a structured detox or cleanse protocol, patients with high oxidative stress burden from illness, chronic stress, or intense exercise, and individuals looking to boost glutathione levels as part of an anti-aging or immune wellness strategy. Our doctors frequently recommend NAC as part of foundational detox and antioxidant protocols.
How to Use
- Serving size: Take 1 capsule two to three times daily
- Timing: Can be taken with or without food; taking with vitamin C may enhance glutathione recycling efficiency
- Duration: Suitable for ongoing daily use; can be used in structured 30–90 day detox cycles as well
- Stacking: Pairs well with Berberine for metabolic and liver support, Super EPA for comprehensive antioxidant and anti-inflammatory coverage, and Basic Nutrients 2/Day for a full foundational protocol
Our Doctors’ Take
Our doctors recommend NAC for a broad range of patient needs — from patients dealing with chronic toxic burden and sluggish detoxification to those focused on respiratory wellness and immune optimization. Glutathione depletion is a common underlying factor in fatigue, poor recovery, and immune vulnerability, and NAC is the most clinically validated and cost-effective way to support the body’s own glutathione production rather than supplementing with glutathione directly, which has absorption challenges.*
*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
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